In one of my classes, we learned about DALY scores. These are basically mathematic equations to quantify the burden of specific diseases. A DALY score is calculated by morbidity and mortality, or in other words:
years living with the disease + years of life lost.
How does one compare living years while deaf vs. being blind? Is hearing or seeing more valuable? How does one numerically compare living 50 years with a permanent hangnail vs. 50 years without a leg? How does one quantify the quality of the years spent living with a disease?
If you had to choose, which would you prefer?